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Briefly, what is nasal high flow therapy?

A patient staying in an intensive care unit has several devices and cables on and around them. High flow oxygen devices can be used under service conditions in order to provide a simpler solution.

High flow oxygen devices consist of a flow-meter, air-oxygen mixer (O2 mixer), gas analyzer and humidifier-heater unit. The device is connected to the patient through a circuit and a nasal cannula made from a softer material than compared to classical cannulas. The device transfers the room air to the patient after mixing it with oxygen, heating it up to the desired degree and humidifying it. You can adjust the flow rate and oxygen concentration of the air provided to the patient. In this way, you are able to transfer oxygen that is at a higher rate than you can provide with normal nasal cannulas, and the desired concentration without causing irritation to the patient. Lower respiratory tract infections are among the leading causes of morbidity and mortality in children across the world. In order to reduce the length of stay as well as morbidity and mortality rates, the hypoxia that might emerge in children with bronchiolitis and pneumonia must be eliminated as soon as possible. Invasive and non-invasive mechanical ventilation (MV) practices are used in patients with respiratory failure. Non-invasive MV has become a more preferred practice due to disadvantages associated with invasive MV and higher risk of complications. In literature, a major portion of suggestions related to non-invasive MV is based on adult studies. However, information and research on non-invasive MV practice in children is limited. Therefore, positive results obtained in vital signs and blood gas values starting from the first hours of therapy as well as absence of deterioration in the vital signs and therapy-related adverse effects in lower respiratory tract infections in babies and children have been evaluated as positive signs in terms of effectiveness and reliability of the high flow oxygen therapy.

GGM HF-2900D Humidiflo® represents a new technology used to offer a high flow therapy at high standards for pediatric and adult patients in hospitals, houses, acute and sub-acute clinical environments.

It consists of a Servo Controlled Flow generator with integrated humidifier and oxygen enrichment systems.

It provides an inspiratory flow up to 60lpm in adult patients. This flow rate not only helps to meet the inspiratory requirements of patients but also provides 99% relative humidity whilst maintaining body temperature.

HF2900D provides for a kinder and effective treatment with pediatric and adult patients in various conditions. HUMIDOFLO helps the patients that can breath on their own but need increased respiratory function by providing an uninterrupted high flow of medical gas to enable a washout of the upper respiratory tract. General respiratory failure, asthma exacerbation, COPD exacerbation, bronchiolitis, pneumonia, and congestive cardiac failure, and premature babies with pediatric respiratory failure are all cases where high flow therapy can be used.


General Areas of Use

1. Hypoxic Respiratory Failure

  • Pneumonia
  • Acute asthma
  • Cardiogenic pulmonary edemam
  • Pulmonary embolism
  • Interstitial lung diseases
  • Critical patients with tracheostomy
  • Obstructive sleep apnea syndrome

2. Cases with high FiO2 requirement

  • Intubation (pre-oxygenation and apneic oxygenation)
  • Respiratory distress after extubation
  • CO poisoning
  • DNR or palliative cases
  • Oxygen support during invasive procedures (BAL, transesophageal ECHO, upper GIS endoscopy, bronchoscopy, etc.)

3. Hypercapnic respiratory failure

  • COPD
  • Idiopathic pulmonary fibrosis

4. Headache

  • Cluster headache
  • Migraine


  1. It can provide higher FiO2 to patients without the need for non-invasive or invasive mechanical ventilation.
  2. It fills the nasopharyngeal dead space, reduces inspiratory resistance and can decrease the work of breathing by this way.
  3. It can enable alveolar strengthening by providing a small amount of CPAP. It can prevent atelectasis.
  4. Humid and warm mucosal oxygen can prevent dehydration; thus, the maintenance of the ciliary activity decreases heat loss and prevents development of tracheitis.
  5. Patients can feed themselves and talk during the therapy.
  6. Even though there are studies showing that invasive mechanical ventilation and re-intubation needs are decreased, there is also research reporting that there is no difference between that and the conventional oxygen therapy.
  7. In a case series performed in an emergency service, patients with dyspnea were switched to high flow oxygen therapy and improvement was observed in oxygen saturation, respiratory frequencies and dyspnea scores.
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